Study Illuminates the Genetic Architecture of Bipolar Disorder

NIH-funded study of people with diverse ancestries revealed new genes involved in the disorder and different genes contributing to specific disorder subtypes March 4, 2025 • Research Highlight Bipolar disorder involves fluctuating periods of manic episodes (marked by extremely “up” or irritable moods) and depressive episodes (marked by very “down” moods or lack of pleasure).…

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Dr. Sarah Hollingsworth Lisanby to Depart NIMH

February 25, 2025 • Institute Update Sarah Hollingsworth “Holly” Lisanby, M.D. This spring, Sarah Hollingsworth “Holly” Lisanby, M.D., Director of the Division of Translational Research (DTR), will depart NIMH to join Arizona State University (ASU) as Founding Dean of the new ASU School of Medicine and Advanced Medical Engineering.Upon joining NIMH in 2015, Dr. Lisanby…

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Novel Sleep-Wake-Based Algorithm Predicts Mood Episodes in Depression, Bipolar Disorder

Summary: Researchers have developed a machine learning-based algorithm that uses sleep-wake data from smartphones and smart bands to predict mood episodes in individuals with depression and bipolar disorder, enabling early intervention and potential prevention of recurrences through lifestyle adjustments. Key Takeaways: Irregular sleep patterns and lifestyle habits can contribute to mood episodes, but individuals may…

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3 Factors Predict Dream Recall, According to Study of 200

Summary: A new study finds that dream recall is influenced by a person’s attitude toward dreaming, proneness to mind-wandering, and sleep patterns, with factors like lighter sleep, younger age, and seasonal variations playing a role, challenging previous assumptions about the effects of age and sex. Key Takeaways:  Three Main Predictors of Dream Recall: Attitude Toward…

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FDA-Cleared Insomnia Treatment Device Now Available to Veterans

Modius Sleep, a US Food and Drug Administration-cleared drug-free insomnia treatment device is now available to veterans through the US Department of Veterans Affairs (VA) program. Developed by Neurovalens, Modius Sleep uses noninvasive neurostimulation to target key brain regions responsible for sleep regulation, helping users fall asleep faster, stay asleep longer, and improve overall sleep…

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CIO: Extinction Sleep Training

What is the cry it out method (extinction sleep training) The Cry-It-Out (CIO) method is a sleep training approach where parents allow their baby to cry for a set period without immediate intervention, with the goal of helping them learn to self-soothe and fall asleep independently. There are two main versions of CIO: Extinction Method…

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Sleep Training Regression

Sleep Training and Sleep Regression Sleep regressions are natural and often coincide with developmental milestones or significant transitions in your baby’s life. Although these phases can temporarily disrupt sleep, gentle sleep training methods can help restore healthy sleep habits. General Sleep Training During Regression Can You Sleep Train a Baby Going Through a Sleep Regression?…

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Why Sleep Training Is Bad:Controversies & Child Bonds

Why Extinction Sleep Training Gets a Bad Name—and How Better Methods Can Work Sleep training is one of the most polarizing topics in parenting. Approaches like unmodified extinction or “Cry It Out” (CIO)—where caregivers leave their child to cry without intervention—are widely criticized for their harshness and emotional toll. For many parents, the idea of…

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