Pre-Application Webinar: Effectiveness and Services Trials

Date and Time December 3, 20241:30–3:00 p.m. ET OverviewThis webinar will provide the scientific field and NIMH scientific reviewers with updated information on clinical trials, including changes to pilot effectiveness and services research. The webinar will cover:PAR-25-285 Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)PAR-25-177 Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions…

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Even With Enough Sleep, Irregular Sleep Patterns Raise Heart Risks

Summary: New research published in the Journal of Epidemiology & Community Health reveals that irregular sleep-wake patterns increase the risk of major cardiovascular events, such as heart attacks and strokes, regardless of whether individuals meet the recommended nightly sleep duration. The study analyzed data from over 72,000 adults and found that those with highly irregular…

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​​How OSA, Obesity, and Metabolic Syndrome Interact to Increase Cardiovascular Risks

Summary: The new review explores the complex relationship between obstructive sleep apnea (OSA), obesity, and metabolic syndrome, emphasizing their mutual reinforcement and shared risk factors, such as visceral fat and aging. It discusses how OSA contributes to cardiovascular risks, including hypertension, type 2 diabetes, and dyslipidemia, through mechanisms like intermittent hypoxia and sympathetic nervous activation.…

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