Panthera Launches Single-Step Ordering and Appliance Design System for OAT

Summary: Panthera Dental has introduced BioMatch, a system designed to simplify the ordering and production of oral appliances for obstructive sleep apnea treatment. The system integrates with intraoral scanners, allowing dentists to order appliances in a single step, which may reduce ordering time and chairside adjustments. BioMatch combines Panthera’s design software with advanced manufacturing technology…

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Can Boosting Cerebrospinal Fluid During Sleep to Prevent Neurodegeneration?

Summary: The Corundum Convergence Institute has awarded a research grant to MIT’s Laura Lewis, PhD, to study how sensory stimulation during sleep can enhance cerebrospinal fluid (CSF) flow in aging brains. Since disordered CSF flow is linked to neurodegenerative diseases, the project aims to develop personalized, non-invasive interventions that could prevent cognitive decline before symptoms…

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Incannex Forms Clinical Advisory Board to Guide IHL-42X Sleep Apnea Drug Development

Summary: Incannex Healthcare has established an Obstructive Sleep Apnea Clinical Advisory Board to support the development of IHL-42X, its investigational oral therapy for sleep apnea. The newly formed board includes Alison Wimms, PhD, who will represent ResMed. IHL-42X, a fixed-dose combination of acetazolamide and dronabinol, is currently in a global phase 2/3 clinical trial (RePOSA),…

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Restless Legs Syndrome Is Incurable – Here’s How to Manage the Symptoms

Adam Taylor, Lancaster University Restless legs syndrome (RLS), also known as Willis-Ekbom Disease, is a neurological condition that affects about 7% of people. Typical symptoms include an irresistible urge to move your legs, alongside sensations of aching, crawling, creeping, itching, pulling or throbbing. Until the age of 35, the condition is equally common in men…

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How Sleep Helps Lock in Positively Charged Memories

Summary: Researchers at the RIKEN Center for Brain Science have discovered that perceptual memories linked to positive emotions are strengthened during sleep, with non-REM sleep—rather than REM sleep—playing a key role. Using a mouse model, the study found that sensory memories associated with positive experiences lasted longer due to reactivation of a brain circuit involving…

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