The apostle John gives us a phrase full of angst when he writes, “whenever our heart condemns us . . .” (1 John 3:20). Has your heart ever condemned you; shut up your happiness in a coffin? Has it replayed your sin on the big screen and made you watch it on repeat? “Whenever our…
Summary: SleepImage (MyCardio LLC), in collaboration with the Sleep Research Society Foundation, has announced the recipients of its “Sleep Equity for Global Health” research grants for 2024. The awarded projects aim to address disparities in sleep health across diverse populations, focusing on under-researched areas that could impact global public health. The grants were awarded to…
Summary: In response to the often overwhelming and stressful online content surrounding baby sleep, experts have launched a mission to combat parent shaming and fear-mongering. The initiative aims to provide evidence-based, compassionate guidance that empowers parents without adding guilt or anxiety. The experts emphasize the importance of understanding each baby’s unique needs and promoting realistic…
Summary: HoneyNaps has published a study in Digital Health validating the effectiveness of its AI-powered diagnostic algorithm, Somnum, for detecting sleep apnea. The study, conducted with 1,000 patients across various levels of sleep-disordered breathing, demonstrated that Somnum achieved high sensitivity and specificity in interpreting polysomnography results. The algorithm showed strong predictive accuracy for diagnosing mild,…
Summary: As people age, their sleep patterns tend to change, often becoming shorter and more fragmented. According to Alicia Roth, PhD, a sleep psychologist at the Cleveland Clinic, these changes are common but not necessarily permanent. Sleep disturbances, such as reduced deep sleep and frequent nighttime awakenings, are reported by over half of adults aged…
Summary: The American Academy of Sleep Medicine (AASM) has released updated clinical practice guidelines for treating restless legs syndrome (RLS). These new recommendations reflect the latest scientific evidence gathered over the past decade. Key updates include a stronger emphasis on evaluating and treating iron deficiency in patients with RLS and a shift away from long-term…
Summary: Tonix Pharmaceuticals has submitted a New Drug Application (NDA) to the US Food and Drug Administration (FDA) for TNX-102 SL, a once-daily sublingual tablet designed to improve sleep, reduce pain, and alleviate other symptoms in fibromyalgia patients. The submission is supported by positive results from two phase 3 studies showing reductions in pain and…
Summary: Nxera Pharma, formerly known as Sosei Group, announced that its partner Centessa Pharmaceuticals has initiated a phase 2 trial of ORX750, an oral orexin receptor 2 agonist designed to treat narcolepsy type 1, type 2, and idiopathic hypersomnia. This milestone results in a $3.5 million payment to Nxera, which will be recognized as revenue…
Summary: Axsome Therapeutics reported growth in its sleep medicine portfolio for the third quarter of 2024, driven by increased uptake of its wake-promoting drug, Sunosi. The company also highlighted progress in its late-stage clinical trials for AXS-12 (targeting narcolepsy) and solriamfetol (targeting shift work disorder, ADHD, and other conditions). Axsome plans to release key trial…
Summary: Centessa Pharmaceuticals announced its third-quarter financial results and updates to its development pipeline, including positive interim data from its phase 1 study of ORX750, an orexin receptor 2 agonist aimed at treating narcolepsy type 1 (NT1), narcolepsy type 2 (NT2), and idiopathic hypersomnia (IH). Following promising results, Centessa has initiated a phase 2a clinical…