SleepScore Labs Partners with US Insurer to Incentivize Sleep Tracking

Summary: SleepScore Labs partnered with a US insurer to integrate sleep tracking and personalized coaching into an existing fitness incentive program, offering participants monetary rewards for tracking their sleep and maintaining consistent sleep habits. The initiative led to improvements in both sleep quality and fitness engagement, with a large portion of participants showing measurable benefits…

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Tomato-Derived Melatonin Ingredient Achieves Self-Affirmed GRAS Status

Summary: A tomato-derived melatonin ingredient, Somato, has achieved self-affirmed Generally Recognized As Safe (GRAS) status in the US. This plant-based alternative to synthetic melatonin is extracted using a proprietary process and has gained traction internationally, particularly in regions where synthetic melatonin is regulated. According to Nutraland USA, the GRAS designation solidifies its potential for broader…

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ORX750 Significantly Increased Wakefulness in Sleep-Deprived Individuals

Summary: Centessa Pharmaceuticals announced positive interim data from its ongoing phase 1 trial of ORX750, an orexin receptor 2 agonist, in acutely sleep-deprived healthy volunteers. The trial demonstrated that ORX750 significantly increased wakefulness, with the 2.5 mg dose restoring normative wakefulness in participants. ORX750 showed a favorable safety and tolerability profile, with no adverse events…

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Epilepsy Drug Slashes Breathing Pauses in OSA Patients

Summary: A clinical trial presented at the European Respiratory Society Congress in Vienna revealed that the epilepsy drug sulthiame significantly reduced symptoms of obstructive sleep apnea (OSA) in patients who cannot tolerate CPAP therapy. The study, conducted across multiple centers in Europe, found that sulthiame led to a reduction in respiratory pauses and improved oxygen…

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Can Wearable Sleep Devices Flag Early Signs of Alzheimer’s Disease?

Summary: The National Institutes of Health awarded $3.9 million to Joyita Dutta, PhD, at UMass Amherst to investigate whether wearable sleep trackers can detect early signs of Alzheimer’s disease by correlating sleep patterns with blood biomarkers. The study will monitor sleep patterns in at-risk individuals using devices like the Apple Watch and Oura Ring, aiming…

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